Treatment For Cancer Cd47

Glowing Mouse Tumours - YouTube
Glowing mouse tumours Nature Newsteam. Subscribe Subscribed Unsubscribe 5,042 5K. Loading Japanese researchers have developed a probe for ovarian cancer that can be sprayed onto tissue during surgery, CD47 Antibody treatment shrinks or eliminates human cancer tumors in mice ... View Video

Gene Silencing In Cancer Therapy - Cosmos UC Davis
Gene Silencing in Cancer Therapy Targeting the CD47 gene to prevent tumor growth Rohan Grover ... Content Retrieval

On The Mechanism Of CD47 Targeting In cancer - PNAS
LETTER On the mechanism of CD47 targeting in cancer The report by Willingham et al. (1) is the most recent in a series of publications from the same group, in which the interaction ... Fetch Here

CD47 In The Tumor Microenvironment Limits Cooperation Between ...
CD47 in the Tumor Microenvironment Limits Cooperation between Antitumor T-cell Immunity and Radiotherapy tumors ofmicetreated withthecombination treatment of IR and CD47 morpholino showed a 96% reduction in tumor Most studies to date concerning the role of CD47 in cancer ... Fetch Doc

A Function-blocking CD47 Antibody Suppresses Stem Cell And ...
Keywords: CD47, cancer stem cells, triple-negative breast cancer, epidermal growth factor receptor, therapeutic antibodies Received: treatment with the CD47 ligand thrombospondin-1 was recently reported to inhibit proliferation, sphere formation, ... Return Doc

Therapeutic Targeting Of The Thrombospondin-1 Receptor CD47 ...
BITS AND BYTES Therapeutic targeting of the thrombospondin-1 receptor CD47 to treat liver cancer David D. Roberts & Sukhbir Kaur & David R. Soto-Pantoja ... Get Doc

CD47 Antibody Inhibits Tumor Recurrence In A Clinical ...
Title: CD47 antibody inhibits tumor recurrence in a clinical relevant glioblastoma animal model Author: Huaiyang Zhu Subject: Journal for ImmunoTherapy of Cancer 2015, 3:P249. doi:10.1186/2051-1426-3-S2-P249 ... Doc Viewer

Endoscopic Molecular Imaging Of Human Bladder cancer Using A ...
Endoscopic molecular imaging of human bladder cancer using anti-CD47–Qdot 625 and blue light cystoscopy. In a bladder with a history of BCG treatment, anti-CD47 –Qdot 625 did not bind to a region with underlying granulomatous cystitis but did bind ... View Doc

CD47: A Potential Immunotherapy Target For Eliminating cancer ...
For potential cancer cell treatment. The role of CD47 in innate immunity The role of CD47 in macrophages Macrophages are the hub of innate immunity system. Their primary duty is to recognize and clear foreign, damaged or aged cells via phagocytosis to keep internal environment ... Get Document

Antibody Therapy Targeting The CD47 Protein Is Effective In A ...
Effective in a model of aggressive metastatic leiomyosarcoma Badreddin Edrisa,b, Kipp Weiskopf c, Regenerative Medicine and the Ludwig Cancer Institute, Stanford University School of Medicine, Stanford, data suggest that treatment with anti-CD47 antibodies not only ... Get Content Here

FOR IMMEDIATE RELEASE NASDAQ:TRIL TSX: TR TRILLIUM ...
TRILLIUM THERAPEUTICS PROVIDES UPDATE ON CD47 PROGRAM Toronto, TRIL; TSX: TR) an immuno-oncology company developing innovative therapies for the treatment of cancer, today announced that it has completed the manufacture of clinical- ... Read Full Source

Therapeutic Antibody Targeting Of CD47 ... - Cancer Research
Therapeutic Antibody Targeting of CD47 Eliminates Human Acute Lymphoblastic Leukemia Mark P. Chao1, Ash A. Alizadeh1,2,3,4, Chad Tang1, anti-CD47 antibody therapy for treatment of human ALL. Cancer Res; 71(4); 1374–84. 2010 AACR. CD47 could eliminate primary human ALL in vitro and in vivo, ... Content Retrieval

Macrophages - Colon Cancer Advice From About.com
Crosstalk Between Colon Cancer Cells and Macrophages Via Inflammatory Mediators and CD47 Promotes Tumour Cell Migration. Symptoms and Diagnosis of Colon Cancer; Colon Cancer Treatment Options; Living with Colon Cancer; ... Read Article

Research Article Correlated Expression Of CD47 And SIRPA In ...
Correlated Expression of CD47 and SIRPA in Breast Cancer M. Nagahara et al. Author manuscripts have been peer reviewed and accepted for publication but have not yet ... Get Content Here

Intravenous Delivery Of SiRNA Targeting CD47 Effectively ...
14% was induced by CD47 siRNA treatment versus 2% in control siRNA treated groups. efficacious and safer approach to target CD47 for cancer therapy. Conclusion Our study using melanoma as a model has conclusively demon- ... Get Doc

CD47 In The Tumor Microenvironment Limits Cooperation Between ...
The radiation growth delay observed with CD47 treatment is dependent on CD8+ T cells in a mouse syngeneic model of fibrosarcoma. Most studies to date concerning the role of CD47 in cancer have focused on the immunosuppressive role of CD47 expression by tumor cells and how reducing this ... Access Doc

HIF-1 Regulates CD47 Expression In Breast cancer Cells To ...
Cancer stem cells, and CD47 deficiency led to cancer stem cell de-pletion. Analysis of datasets derived from thousands of patients with breast cancer revealed that CD47 expression was correlated with HIF target gene expression and with patient mortality. ... Retrieve Here

COMMENTARY Perspectives On Anti-CD47 Antibody treatment For ...
COMMENTARY Perspectives on anti-CD47 antibody treatment for experimental cancer Emil R. Unanue1 Department of Pathology and Immunology, Washington University School of Medicine, ... Access Full Source

CD117 - Wikipedia, The Free Encyclopedia
Also known as proto-oncogene c-Kit or tyrosine-protein kinase Kit or CD117, is a receptor tyrosine kinase protein that in humans is encoded by the KIT gene. [1] a cancer of hematopoietic progenitors, CD47; CD48; CD49. a; b; c; d; e; f; CD50; 51-100: CD51; CD52; CD53; CD54; CD55; CD56 ... Read Article

CD47 Is An Adverse Prognostic Factor And Therapeutic Antibody ...
CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Stanford Cancer Center, and Ludwig Center at Stanford ment in vivo. Finally, treatment of human AML LSC-engrafted mice with anti-CD47 antibody depleted ... Visit Document

PTPRC - Wikipedia, The Free Encyclopedia
Protein tyrosine phosphatase, receptor type, C also known as PTPRC is an enzyme that, in humans, is encoded by the PTPRC gene. [1] PTPRC is also known as CD45 antigen CD47; CD48; CD49. a; b; c; d; e; f; CD50; 51-100: CD51; CD52; CD53; CD54; CD55; CD56; CD57; CD58; CD59; CD61; CD62. E; L; P ... Read Article

CD47 Blockade Triggers T Cell–mediated Destruction Of ...
Anti-CD47 treatment and standard-of-care chemotherapy must be . properly timed and tested, Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages . primes an effective antitumor T-cell response. Proc. Natl. Acad. Sci. USA. 110, 11103–11108 (2013). ... Get Document

The Prognostic Role Of CD47 In Triple Negative Breast Cancer ...
Omobolaji Akala, MD, PhD CRC IRB Proposal August 2011 The prognostic role of CD47 in Triple negative Breast Cancer 1). Study Purpose and Rationale ... View Document